Endocrine Abstracts

Acromegaly is a rare disease usually diagnosed late in disease evolution. It implies for skeletal changes of most flat bones including those of the skull. Consequently, a progressive facial disfiguration occurs at slow velocity of irreversible nature. Even after curation most of these changes stay for the whole life of the patient.Aim: to study the potential relationship between disfiguring facial modifications and psychosocial and Quality of Life (QoL) ...

Background: Cross-sectional studies performed to estimate the prevalence (Prev) of thyroid dysfunctions are expensive and involve a great effort. Diagnosis and therapeutic prescription records may be a good alternative to monitor such prevalence. They also allow to easily compare the thyroid dysfunctions prevalence of among different populations (EUthyroid Project).Objective: 1) To estimate the Prev of hypothyroidism (hypoT) and hyperthyroidism (hyperT) ...

Background: Patients with type 2 diabetes mellitus (T2DM) have an increased risk of fragility fractures. Anti-diabetic oral agents and insulin may also impact on fracture risk. There is however scarce data available on the effect of such therapies combined as usually prescribed in real-life practice conditions.Objectives: The objective of this study was to compare the risk of fracture among T2DM patients who are users of different antidiabetic treatments...

Introduction: Patients with type 1 diabetes mellitus (DM1) present a high prevalence of autoimmune associated diseases. Recently, we described a prevalence of latent pernicious anemia (LPA) of 12.4% in DM1.Objectives: A 5-year follow-up study of a cohort of DM1 patients in order to evaluate the evolution of biochemical markers of LPA, defined as a serum pepsinogen I (PI) concentration below normal limits.Material and methods: One h...

Background: An association of pregnancy outcomes with subclinical hypothyroidism have been reported, however, there still exists a strong controversy regarding whether subclinical hypothyroidism ought to be dealt with or not. The latest American Thyroid Association’s guideline gives support to a higher TSH upper reference range of 4 mIU/l than the one proposed a few years ago of 2.5 mIU/l for the first trimester of pregnancy, in the absence of local normal ranges of TSH. ...